Clonotypic Composition of the CD4(+) T Cell Response to a Vectored Retroviral Antigen Is Determined by Its Speed

The mechanisms whereby different vaccines may expand distinct Ag-specific T cell clonotypes or induce disparate degrees of protection are incompletely understood. We found that several delivery modes of a model retroviral Ag, including natural infection, preferentially expanded initially rare high-a...

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Bibliografiska uppgifter
Huvudupphovsmän: Thorborn, Georgina, Ploquin, Mickaël J., Eksmond, Urszula, Pike, Rebecca, Bayer, Wibke, Dittmer, Ulf, Hasenkrug, Kim J., Pepper, Marion, Kassiotis, George
Materialtyp: Artigo
Språk:Inglês
Publicerad: AAI 2014
Ämnen:
Antigen Recognition and Responses
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119786/
https://ncbi.nlm.nih.gov/pubmed/25000983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400667
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