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Antigen-specific naïve CD8(+) T cells produce a single pulse of IFNγ in vivo within hours of infection, but without antiviral effect
In vitro studies have shown that naïve CD8(+) T cells are unable to express most of their effector proteins until after at least one round of cell division has taken place. We have re-assessed this issue in vivo, and find that naïve CD8(+) T cells mount antigen-specific responses within hours of inf...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4119517/ https://ncbi.nlm.nih.gov/pubmed/25015828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400348 |
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