The anticancer gene ORCTL3 targets stearoyl-CoA desaturase-1 for tumour-specific apoptosis

ORCTL3 is a member of a group of genes, the so-called anticancer genes, that cause tumour-specific cell death. We show that this activity is triggered in isogenic renal cells upon their transformation independently of the cells’ proliferation status. For its cell death effect ORCTL3 targets the enzy...

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Bibliografiske detaljer
Main Authors: AbuAli, G, Chaisaklert, W, Stelloo, E, Pazarentzos, E, Hwang, M-S, Qize, D, Harding, SV, Al-Rubaish, A, Alzahrani, A-H, Al-Ali, A, Sanders, TAB, Aboagye, E O, Grimm, S
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119473/
https://ncbi.nlm.nih.gov/pubmed/24769897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.93
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