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Estimation and partitioning of (co)heritability of inflammatory bowel disease from GWAS and immunochip data
As custom arrays are cheaper than generic GWAS arrays, larger sample size is achievable for gene discovery. Custom arrays can tag more variants through denser genotyping of SNPs at associated loci, but at the cost of losing genome-wide coverage. Balancing this trade-off is important for maximizing e...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4119411/ https://ncbi.nlm.nih.gov/pubmed/24728037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu174 |
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