TSC2 epigenetic defect in primary LAM cells. Evidence of an anchorage-independent survival

Tuberous sclerosis complex (TSC) is caused by mutations in TSC1 or TSC2 genes. Lymphangioleiomyomatosis (LAM) can be sporadic or associated with TSC and is characterized by widespread pulmonary proliferation of abnormal α-smooth muscle (ASM)-like cells. We investigated the features of ASM cells isol...

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Bibliografiska uppgifter
Huvudupphovsmän: Lesma, Elena, Ancona, Silvia, Sirchia, Silvia M, Orpianesi, Emanuela, Grande, Vera, Colapietro, Patrizia, Chiaramonte, Eloisa, Di Giulio, Anna Maria, Gorio, Alfredo
Materialtyp: Artigo
Språk:Inglês
Publicerad: BlackWell Publishing Ltd 2014
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Original Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119383/
https://ncbi.nlm.nih.gov/pubmed/24606538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12237
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