TSC2 epigenetic defect in primary LAM cells. Evidence of an anchorage-independent survival

Tuberous sclerosis complex (TSC) is caused by mutations in TSC1 or TSC2 genes. Lymphangioleiomyomatosis (LAM) can be sporadic or associated with TSC and is characterized by widespread pulmonary proliferation of abnormal α-smooth muscle (ASM)-like cells. We investigated the features of ASM cells isol...

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書誌詳細
主要な著者: Lesma, Elena, Ancona, Silvia, Sirchia, Silvia M, Orpianesi, Emanuela, Grande, Vera, Colapietro, Patrizia, Chiaramonte, Eloisa, Di Giulio, Anna Maria, Gorio, Alfredo
フォーマット: Artigo
言語:Inglês
出版事項: BlackWell Publishing Ltd 2014
主題:
Original Articles
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119383/
https://ncbi.nlm.nih.gov/pubmed/24606538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12237
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