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Deletion of the NMDA Receptor GluN2A Subunit Significantly Decreases Dendritic Growth in Maturing Dentate Granule Neurons

It is known that NMDA receptors can modulate adult hippocampal neurogenesis, but the contribution of specific regulatory GluN2 subunits has been difficult to determine. Here we demonstrate that mice lacking GluN2A (formerly NR2A) do not show altered cell proliferation or neuronal differentiation, bu...

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Hlavní autoři: Kannangara, Timal S., Bostrom, Crystal A., Ratzlaff, Andrea, Thompson, Lee, Cater, Robyn M., Gil-Mohapel, Joana, Christie, Brian R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118862/
https://ncbi.nlm.nih.gov/pubmed/25083703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103155
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