Rapid Phenotypic and Genomic Change in Response to Therapeutic Pressure in Prostate Cancer Inferred by High Content Analysis of Single Circulating Tumor Cells

Timely characterization of a cancer's evolution is required to predict treatment efficacy and to detect resistance early. High content analysis of single Circulating Tumor Cells (CTCs) enables sequential characterization of genotypic, morphometric and protein expression alterations in real time...

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Main Authors: Dago, Angel E., Stepansky, Asya, Carlsson, Anders, Luttgen, Madelyn, Kendall, Jude, Baslan, Timour, Kolatkar, Anand, Wigler, Michael, Bethel, Kelly, Gross, Mitchell E., Hicks, James, Kuhn, Peter
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2014
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118839/
https://ncbi.nlm.nih.gov/pubmed/25084170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101777
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