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Crystallization and preliminary crystallographic study of human coronavirus NL63 main protease in complex with an inhibitor

Human coronavirus NL63 mainly infects younger children and causes cough, fever, rhinorrhoea, bronchiolitis and croup. It encodes two polyprotein precursors required for genome replication and transcription. Each polyprotein undergoes extensive proteolytic processing, resulting in functional subunits...

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Detalhes bibliográficos
Main Authors: Wang, Fenghua, Tan, Yusheng, Li, Huiyan, Chen, Xia, Wang, Jinshan, Li, Shuang, Fu, Sheng, Zhao, Qi, Chen, Cheng, Su, Dan, Yang, Haitao
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118806/
https://ncbi.nlm.nih.gov/pubmed/25084384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X14012953
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