Crystallization and preliminary crystallographic study of human coronavirus NL63 main protease in complex with an inhibitor

Human coronavirus NL63 mainly infects younger children and causes cough, fever, rhinorrhoea, bronchiolitis and croup. It encodes two polyprotein precursors required for genome replication and transcription. Each polyprotein undergoes extensive proteolytic processing, resulting in functional subunits...

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Autors principals: Wang, Fenghua, Tan, Yusheng, Li, Huiyan, Chen, Xia, Wang, Jinshan, Li, Shuang, Fu, Sheng, Zhao, Qi, Chen, Cheng, Su, Dan, Yang, Haitao
Format: Artigo
Idioma:Inglês
Publicat: International Union of Crystallography 2014
Matèries:
Crystallization Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118806/
https://ncbi.nlm.nih.gov/pubmed/25084384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X14012953
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