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Total Synthesis of Maoecrystal V: Early-Stage C–H Functionalization and Lactone Assembly by Radical Cyclization

A total synthesis of the unusual ent-kaurane maoecrystal V is described. The synthesis strategy features a counterintuitive early disconnection of the lactone subunit to a polycyclic enol ether intermediate in order to preserve the central tetrahydrofuran ring until the beginning stages of the synth...

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Detalhes bibliográficos
Main Authors: Lu, Ping, Gu, Zhenhua, Zakarian, Armen
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118676/
https://ncbi.nlm.nih.gov/pubmed/24047444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja408231t
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