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Coupling the Torpedo Microplate-Receptor Binding Assay with Mass Spectrometry to Detect Cyclic Imine Neurotoxins

Cyclic imine neurotoxins constitute an emergent family of neurotoxins of dinoflagellate origin that are potent antagonists of nicotinic acetylcholine receptors. We developed a target-directed functional method based on the mechanism of action of competitive agonists/antagonists of nicotinic acetylch...

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Detalhes bibliográficos
Main Authors: Aráoz, Rómulo, Ramos, Suzanne, Pelissier, Franck, Guérineau, Vincent, Benoit, Evelyne, Vilariño, Natalia, Botana, Luis M., Zakarian, Armen, Molgó, Jordi
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118673/
https://ncbi.nlm.nih.gov/pubmed/23131021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac3027564
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