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Mechanical feedback through E-cadherin promotes direction sensing during collective cell migration
E-cadherin is a major homophilic cell-cell adhesion molecule that inhibits motility of individual cells on matrix. However its contribution to migration of cells through cell-rich tissues is less clear. We developed an in vivo sensor of mechanical tension across E-cadherin molecules, which we combin...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4118667/ https://ncbi.nlm.nih.gov/pubmed/24855950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.03.045 |
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