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Morphological defects in a Novel Rdh10 Mutant that has Reduced Retinoic Acid Biosynthesis and Signaling

Retinoic acid (RA) signaling is necessary for proper patterning and morphogenesis during embryonic development. Tissue specific RA signaling requires precise spatial and temporal synthesis of RA from retinal by retinaldehyde dehydrogenases (Raldh) and the conversion of retinol to retinal by retinol...

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Detalhes bibliográficos
Main Authors: Ashique, Amir M., May, Scott R., Kane, Maureen A., Folias, Alexandra E., Phamluong, Khanhky, Choe, Youngshik, Napoli, Joseph L., Peterson, Andrew S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118640/
https://ncbi.nlm.nih.gov/pubmed/22162152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.22002
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