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Cerebrovascular defects in Foxc1 mutants correlate with aberrant WNT and VEGF-A pathways downstream of retinoic acid from the meninges

Growth and maturation of the cerebrovasculature is a vital event in neocortical development however mechanisms that control cerebrovascular development remain poorly understood. Mutations in or deletions that include the FOXC1 gene are associated with congenital cerebrovascular anomalies and increas...

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Detalhes bibliográficos
Publicado no:Dev Biol
Main Authors: Mishra, Swati, Choe, Youngshik, Pleasure, Samuel J., Siegenthaler, Julie A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5124406/
https://ncbi.nlm.nih.gov/pubmed/27671872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2016.09.019
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