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The Hippo effector Yorkie activates transcription by interacting with a histone methyltransferase complex through Ncoa6

The Hippo signaling pathway regulates tissue growth in Drosophila through the transcriptional coactivator Yorkie (Yki). How Yki activates target gene transcription is poorly understood. Here, we identify Nuclear receptor coactivator 6 (Ncoa6), a subunit of the Trithorax-related (Trr) histone H3 lysi...

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Hlavní autoři: Qing, Yun, Yin, Feng, Wang, Wei, Zheng, Yonggang, Guo, Pengfei, Schozer, Frederick, Deng, Hua, Pan, Duojia
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118621/
https://ncbi.nlm.nih.gov/pubmed/25027438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02564
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