Both chains of HLA-DR bind to the membrane with a penultimate hydrophobic region and the heavy chain is phosphorylated at its hydrophilic carboxyl terminus.

Ítems similars

• Detergent-soluble HLA antigens contain a hydrophilic region at the COOH-terminus and a penultimate hydrophobic region.
  per: Springer, T A, et al.
  Publicat: (1976)
• cDNA clones for the heavy chain of HLA-DR antigens obtained after immunopurification of polysomes by monoclonal antibody.
  per: Korman, A J, et al.
  Publicat: (1982)
• Immunoglobulin receptor signaling depends on the carboxyl terminus but not the heavy-chain class.
  per: Webb, C F, et al.
  Publicat: (1989)
• The amino acid sequence and gene organization of the heavy chain of the HLA-DR antigen: homology to immunoglobulins.
  per: Korman, A J, et al.
  Publicat: (1982)
• cDNA clone for the heavy chain of the human B cell alloantigen DC1: strong sequence homology to the HLA-DR heavy chain.
  per: Auffray, C, et al.
  Publicat: (1982)