Detergent-soluble HLA antigens contain a hydrophilic region at the COOH-terminus and a penultimate hydrophobic region.

Purified, detergent-soluble HLA antigens (p44,12) are composed of a glycoprotein of molecular weight 44,000 (p44) and a peptide of molecular weight 12,000 (p12), beta2-microglobulin. Upon digestion with papain, p44,12 is converted to p39,12, then to p34,12, which retains antigenic activity. The NH2-...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Springer, T A, Strominger, J L
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1976
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC430616/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/781677/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.73.7.2481
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