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Detergent-soluble HLA antigens contain a hydrophilic region at the COOH-terminus and a penultimate hydrophobic region.

Purified, detergent-soluble HLA antigens (p44,12) are composed of a glycoprotein of molecular weight 44,000 (p44) and a peptide of molecular weight 12,000 (p12), beta2-microglobulin. Upon digestion with papain, p44,12 is converted to p39,12, then to p34,12, which retains antigenic activity. The NH2-...

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Detalhes bibliográficos
Main Authors: Springer, T A, Strominger, J L
Formato: Artigo
Idioma:Inglês
Publicado em: 1976
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC430616/
https://ncbi.nlm.nih.gov/pubmed/781677
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