PDE5 inhibition alleviates functional muscle ischemia in boys with Duchenne muscular dystrophy

OBJECTIVE: To determine whether phosphodiesterase type 5 (PDE5) inhibition can alleviate exercise-induced skeletal muscle ischemia in boys with Duchenne muscular dystrophy (DMD). METHODS: In 10 boys with DMD and 10 healthy age-matched male controls, we assessed exercise-induced attenuation of reflex...

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Main Authors: Nelson, Michael D., Rader, Florian, Tang, Xiu, Tavyev, Jane, Nelson, Stanley F., Miceli, M. Carrie, Elashoff, Robert M., Sweeney, H. Lee, Victor, Ronald G.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Lippincott Williams & Wilkins 2014
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118495/
https://ncbi.nlm.nih.gov/pubmed/24808022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000000498
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