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DNA gyrase: purification and catalytic properties of a fragment of gyrase B protein.

A protein isolated from Escherichia coli complements the DNA gyrase A (NalA) protein to generate an activity that relaxes supercoiled DNA. Oxolinic acid, a known inhibitor of DNA gyrase, blocks this activity and causes double-strand cleavage of DNA at the same sites as are attacked by DNA gyrase. Th...

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Detalhes bibliográficos
Main Authors: Gellert, M, Fisher, L M, O'Dea, M H
Formato: Artigo
Idioma:Inglês
Publicado em: 1979
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC411849/
https://ncbi.nlm.nih.gov/pubmed/230505
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