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The Gut Hormone Ghrelin Partially Reverses Energy Substrate Metabolic Alterations in the Failing Heart

BACKGROUND: The gut-derived hormone ghrelin, especially its acylated form, plays a major role in the regulation of systemic metabolism and exerts also relevant cardioprotective effects, hence it has been proposed for the treatment of heart failure (HF). We tested the hypothesis that ghrelin can dire...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mitacchione, Gianfranco, Powers, Jeffrey C., Grifoni, Gino, Woitek, Felix, Ly, Amy Lam; Lien, Settanni, Fabio, Makarewich, Catherine A., McCormick, Ryan, Trovato, Letizia, Houser, Steven R., Granata, Riccarda, Recchia, Fabio A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118426/
https://ncbi.nlm.nih.gov/pubmed/24855152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.114.001167
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