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Kinetic Hairpin Oligonucleotide Blockers for Selective Amplification of Rare Mutations

Detection of rare mutant alleles in an excess of wild type alleles is increasingly important in cancer diagnosis. Several methods for selective amplification of a mutant allele via the polymerase chain reaction (PCR) have been reported, but each of these methods has its own limitations. A common pro...

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Detalhes bibliográficos
Main Authors: Jia, Yanwei, Sanchez, J. Aquiles, Wangh, Lawrence J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118197/
https://ncbi.nlm.nih.gov/pubmed/25082368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05921
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