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Kinetic Hairpin Oligonucleotide Blockers for Selective Amplification of Rare Mutations
Detection of rare mutant alleles in an excess of wild type alleles is increasingly important in cancer diagnosis. Several methods for selective amplification of a mutant allele via the polymerase chain reaction (PCR) have been reported, but each of these methods has its own limitations. A common pro...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4118197/ https://ncbi.nlm.nih.gov/pubmed/25082368 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05921 |
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