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Binding of cis- and trans-dichlorodiammineplatinum(II) to the nucleosome core

The binding of the antitumor drug cis-dichlorodiammineplatinum(II) and its inactive trans isomer with the nucleosome core particle has been investigated. Kinetic studies show that platinum binding increases with incubation time, from a few bound platinum atoms per nucleosome core in the first 0.5 hr...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lippard, Stephen J., Hoeschele, James D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1979
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC411808/
https://ncbi.nlm.nih.gov/pubmed/293706
Tagiau: Ychwanegu Tag
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