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Sex Modifies the APOE-Related Risk of Developing Alzheimer's Disease

OBJECTIVE: The APOE4 allele is the strongest genetic risk factor for sporadic Alzheimer’s disease (AD). Case-control studies suggest the APOE4 link to AD is stronger in women. We examined the APOE4-by-sex interaction in conversion risk (from healthy aging to mild cognitive impairment (MCI)/AD or fro...

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Detalhes bibliográficos
Main Authors: Altmann, Andre, Tian, Lu, Henderson, Victor W, Greicius, Michael D
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4117990/
https://ncbi.nlm.nih.gov/pubmed/24623176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24135
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