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Viral transduction of primary Schwann cells using a Cre-lox system to regulate GDNF expression

Glial cell-line-derived neurotrophic factor (GDNF) is a potent neurotrophic factor known to enhance motor nerve regeneration following its delivery. However, recent studies have determined that extended GDNF delivery to regenerating axons can entrap motor axons at the site of GDNF delivery. This ent...

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Detalhes bibliográficos
Main Authors: Wu-Fienberg, Yuewei, Moore, Amy M., Marquardt, Laura M., Newton, Piyaraj, Johnson, Philip J., Mackinnon, Susan E., Sakiyama-Elbert, Shelly E., Wood, Matthew D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4117799/
https://ncbi.nlm.nih.gov/pubmed/24728940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.25247
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