Human ISWI complexes are targeted by SMARCA5 ATPase and SLIDE domains to help resolve lesion-stalled transcription

Chromatin compaction of deoxyribonucleic acid (DNA) presents a major challenge to the detection and removal of DNA damage. Helix-distorting DNA lesions that block transcription are specifically repaired by transcription-coupled nucleotide excision repair, which is initiated by binding of the CSB pro...

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Autors principals: Aydin, Özge Z., Marteijn, Jurgen A., Ribeiro-Silva, Cristina, Rodríguez López, Aida, Wijgers, Nils, Smeenk, Godelieve, van Attikum, Haico, Poot, Raymond A., Vermeulen, Wim, Lans, Hannes
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
Matèries:
Genome Integrity, Repair and Replication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4117783/
https://ncbi.nlm.nih.gov/pubmed/24990377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku565
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