Two non-synonymous markers in PTPN21, identified by genome-wide association study data-mining and replication, are associated with schizophrenia

We conducted data-mining analyses of genome wide association (GWA) studies of the CATIE and MGS-GAIN datasets, and found 13 markers in the two physically linked genes, PTPN21 and EML5, showing nominally significant association with schizophrenia. Linkage disequilibrium (LD) analysis indicated that a...

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Detalhes bibliográficos
Main Authors: Chen, Jingchun, Lee, Grace, Fanous, Ayman H., Zhao, Zhongming, Jia, Peilin, O'Neill, Anthony, Walsh, Dermot, Kendler, Kenneth S., Chen, Xiangning
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4117700/
https://ncbi.nlm.nih.gov/pubmed/21752600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.schres.2011.06.023
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