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Convergent roles of de novo mutations and common variants in schizophrenia in tissue-specific and spatiotemporal co-expression network

Genetic components susceptible to complex disease such as schizophrenia include a wide spectrum of variants, including common variants (CVs) and de novo mutations (DNMs). Although CVs and DNMs differ by origin, it remains elusive whether and how they interact at the gene, pathway, and network levels...

詳細記述

保存先:
書誌詳細
出版年:Transl Psychiatry
主要な著者: Jia, Peilin, Chen, Xiangning, Fanous, Ayman H., Zhao, Zhongming
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5967316/
https://ncbi.nlm.nih.gov/pubmed/29799522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-018-0154-2
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