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Convergent roles of de novo mutations and common variants in schizophrenia in tissue-specific and spatiotemporal co-expression network

Genetic components susceptible to complex disease such as schizophrenia include a wide spectrum of variants, including common variants (CVs) and de novo mutations (DNMs). Although CVs and DNMs differ by origin, it remains elusive whether and how they interact at the gene, pathway, and network levels...

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Bibliografische gegevens
Gepubliceerd in:Transl Psychiatry
Hoofdauteurs: Jia, Peilin, Chen, Xiangning, Fanous, Ayman H., Zhao, Zhongming
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5967316/
https://ncbi.nlm.nih.gov/pubmed/29799522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-018-0154-2
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