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Convergent roles of de novo mutations and common variants in schizophrenia in tissue-specific and spatiotemporal co-expression network

Genetic components susceptible to complex disease such as schizophrenia include a wide spectrum of variants, including common variants (CVs) and de novo mutations (DNMs). Although CVs and DNMs differ by origin, it remains elusive whether and how they interact at the gene, pathway, and network levels...

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Detalhes bibliográficos
Publicado no:Transl Psychiatry
Main Authors: Jia, Peilin, Chen, Xiangning, Fanous, Ayman H., Zhao, Zhongming
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5967316/
https://ncbi.nlm.nih.gov/pubmed/29799522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-018-0154-2
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