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Convergent roles of de novo mutations and common variants in schizophrenia in tissue-specific and spatiotemporal co-expression network

Genetic components susceptible to complex disease such as schizophrenia include a wide spectrum of variants, including common variants (CVs) and de novo mutations (DNMs). Although CVs and DNMs differ by origin, it remains elusive whether and how they interact at the gene, pathway, and network levels...

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Bibliografski detalji
Izdano u:Transl Psychiatry
Glavni autori: Jia, Peilin, Chen, Xiangning, Fanous, Ayman H., Zhao, Zhongming
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5967316/
https://ncbi.nlm.nih.gov/pubmed/29799522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-018-0154-2
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