Caricamento...

Role of thymidylate synthetase activity in development of methotrexate cytotoxicity.

Methotrexate (MTX) inhibition of the growth of mouse or human leukemia cells in culture was partially prevented by either thymidine (dThd) or hypoxanthine. 5-Fluoro-2'-deoxyuridine (FdUrd) also decreased the growth-inhibitory potency of MTX in the presence of small concentrations of 5-formyltet...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Moran, R G, Mulkins, M, Heidelberger, C
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1979
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC411765/
https://ncbi.nlm.nih.gov/pubmed/160558
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !