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Initiation of plasma prorenin activation by Hageman factor-dependent conversion of plasma prekallikrein to kallikrein.

Plasma prorenin is an inactive form of renin (EC 3.4.99.19) that can be converted to active renin in acid-treated plasma by an endogenous serine protease that is active at alkaline pH (alkaline phase activation). To identify this enzyme we first tested the ability of Hageman factor fragments, plasma...

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Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Sealey, J E, Atlas, S A, Laragh, J H, Silverberg, M, Kaplan, A P
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 1979
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC411763/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/42905/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.11.5914
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