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Initiation of plasma prorenin activation by Hageman factor-dependent conversion of plasma prekallikrein to kallikrein.

Plasma prorenin is an inactive form of renin (EC 3.4.99.19) that can be converted to active renin in acid-treated plasma by an endogenous serine protease that is active at alkaline pH (alkaline phase activation). To identify this enzyme we first tested the ability of Hageman factor fragments, plasma...

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Bibliografiske detaljer
Main Authors: Sealey, J E, Atlas, S A, Laragh, J H, Silverberg, M, Kaplan, A P
Format: Artigo
Sprog:Inglês
Udgivet: 1979
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC411763/
https://ncbi.nlm.nih.gov/pubmed/42905
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