Fully Human Antagonistic Antibodies against CCR4 Potently Inhibit Cell Signaling and Chemotaxis

BACKGROUND: CC chemokine receptor 4 (CCR4) represents a potentially important target for cancer immunotherapy due to its expression on tumor infiltrating immune cells including regulatory T cells (T(reg)s) and on tumor cells in several cancer types and its role in metastasis. METHODOLOGY: Using phag...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hagemann, Urs B., Gunnarsson, Lavinia, Géraudie, Solène, Scheffler, Ulrike, Griep, Remko A., Reiersen, Herald, Duncan, Alexander R., Kiprijanov, Sergej M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2014
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4117600/
https://ncbi.nlm.nih.gov/pubmed/25080123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103776
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg