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Discovery of a Potent and Orally Bioavailable CCR2 and CCR5 Dual Antagonist
[Image: see text] This report describes the discovery of a potent, orally bioavailable CC chemokine receptor 2 (CCR2) antagonist which, while optimized for CCR2 potency, also had potent CC chemokine receptor 5 (CCR5) activity.
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| Hlavní autoři: | , , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Chemical Society
2009
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4007850/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml900009d |
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