Discovery of a Potent and Orally Bioavailable CCR2 and CCR5 Dual Antagonist

[Image: see text] This report describes the discovery of a potent, orally bioavailable CC chemokine receptor 2 (CCR2) antagonist which, while optimized for CCR2 potency, also had potent CC chemokine receptor 5 (CCR5) activity.

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Pasternak, Alexander, Goble, Stephen D., Struthers, Mary, Vicario, Pasquale P., Ayala, Julia M., Di Salvo, Jerry, Kilburn, Ruth, Wisniewski, Thomas, DeMartino, Julie A., Mills, Sander G., Yang, Lihu
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Chemical Society 2009
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007850/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml900009d
टैग : टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!

समान संसाधन