Berberine potently attenuates intestinal polyps growth in ApcMin mice and familial adenomatous polyposis patients through inhibition of Wnt signalling

As a traditional anti-inflammatory Chinese herbal medicine, Alkaloid berberine has been recently reported to exhibit anti-tumour effects against a wide spectrum of cancer. However, the mechanism was largely unknown. Gene chip array reveals that with berberine treatment, c-Myc, the target gene of Wnt...

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Bibliographic Details
Main Authors:	Zhang, Junfang, Cao, Hailong, Zhang, Bing, Cao, Hanwei, Xu, Xiuqin, Ruan, Hang, Yi, Tingting, Tan, Li, Qu, Rui, Song, Gang, Wang, Bangmao, Hu, Tianhui
Format:	Artigo
Language:	Inglês
Published:	John Wiley & Sons 2013
Subjects:	Original Articles
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4117561/ https://ncbi.nlm.nih.gov/pubmed/24015932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12119
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Berberine potently attenuates intestinal polyps growth in ApcMin mice and familial adenomatous polyposis patients through inhibition of Wnt signalling

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