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Regulation of the amplification C3 convertase of human complement by an inhibitory protein isolated from human erythrocyte membrane

An activity that is inhibitory to the properdin-stabilized amplification C3 convertase (C3b,Bb,P) was solubilized from human erythrocyte (E(hu)) membranes by Nonidet P-40 and purified to homogeneity. The inhibitory membrane glycoprotein had an apparent M(r) of 1-1.2×10(6) on gel filtration in the pr...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Autor principal: Fearon, Douglas T.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1979
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC411753/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/293688/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.11.5867
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