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Delivery of Bioactive Lipids from Composite Microgel-Microsphere Injectable Scaffolds Enhances Stem Cell Recruitment and Skeletal Repair

In this study, a microgel composed of chitosan and inorganic phosphates was used to deliver poly(lactic-co-glycolic acid) (PLAGA) microspheres loaded with sphingolipid growth factor FTY720 to critical size cranial defects in Sprague Dawley rats. We show that sustained release of FTY720 from injected...

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Detalhes bibliográficos
Main Authors: Das, Anusuya, Barker, Daniel A., Wang, Tiffany, Lau, Cheryl M., Lin, Yong, Botchwey, Edward A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4117484/
https://ncbi.nlm.nih.gov/pubmed/25077607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101276
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