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Biology and Physics of von Willebrand Factor Concatamers
Structural specialisations enable von Willebrand factor (VWF) to assemble during biosynthesis into helical tubules in Weibel-Palade bodies (WPB). Specialisations include a pH-regulated dimeric bouquet formed by the C-terminal half of VWF and helical assembly guided by the N-terminal half that templa...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4117350/ https://ncbi.nlm.nih.gov/pubmed/21781248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2011.04320.x |
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