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Chromosome-scale scaffolding of de novo genome assemblies based on chromatin interactions
Genomes assembled de novo from short reads are highly fragmented relative to the finished chromosomes of H. sapiens and key model organisms generated by the Human Genome Project. To address this, we need scalable, cost-effective methods enabling chromosome-scale contiguity. Here we show that genome-...
Tallennettuna:
| Päätekijät: | , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2013
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4117202/ https://ncbi.nlm.nih.gov/pubmed/24185095 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.2727 |
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