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Conformation, energy, and folding ability of selected amino acid sequences.

Evolutionary selection of sequences is studied with a knowledge-based Hamiltonian to find the design principle for folding to a model protein structure. With sequences selected by naive energy minimization, the model structure tends to be unstable and the folding ability is low. Sequences with high...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Autor principal: Sasai, M
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41172/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7667308/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.18.8438
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