Conformation, energy, and folding ability of selected amino acid sequences.
Evolutionary selection of sequences is studied with a knowledge-based Hamiltonian to find the design principle for folding to a model protein structure. With sequences selected by naive energy minimization, the model structure tends to be unstable and the folding ability is low. Sequences with high...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1995
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41172/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7667308/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.18.8438 |
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