Functional Mapping of Community Acquired Respiratory Distress Syndrome (CARDS) Toxin of Mycoplasma pneumoniae Defines Regions with ADP-ribosyltransferase, Vacuolating, and Receptor-Binding Activities

Community-acquired respiratory distress syndrome (CARDS) toxin from Mycoplasma pneumoniae is a 591 amino acid virulence factor with ADP-ribosyltransferase (ADPRT) and vacuolating activities. It is expressed at low levels during in vitro growth and at high levels during colonization of the lung. Expo...

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Main Authors: Kannan, T. R., Krishnan, Manickam, Ramasamy, Kumaraguruparan, Becker, Argentina, Pakhomova, Olga N., Hart, P. John, Baseman, Joel B.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116743/
https://ncbi.nlm.nih.gov/pubmed/24948331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12680
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