Neuronal Uptake of Nanoformulated Superoxide Dismutase and Attenuation of Angiotensin II-Dependent Hypertension Following Central Administration

Excessive production of superoxide (O(2)(•−)) in the central nervous system has been widely implicated in the pathogenesis of cardiovascular diseases, including chronic heart failure and hypertension. In an attempt to overcome the failed therapeutic impact of currently available antioxidants in card...

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Autori principali: Savalia, Krupa, Manickam, Devika S., Rosenbaugh, Erin G., Tian, Jun, Ahmad, Iman M., Kabanov, Alexander V., Zimmerman, Matthew C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116739/
https://ncbi.nlm.nih.gov/pubmed/24924945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2014.06.001
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