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Neuronal Uptake of Nanoformulated Superoxide Dismutase and Attenuation of Angiotensin II-Dependent Hypertension Following Central Administration

Excessive production of superoxide (O(2)(•−)) in the central nervous system has been widely implicated in the pathogenesis of cardiovascular diseases, including chronic heart failure and hypertension. In an attempt to overcome the failed therapeutic impact of currently available antioxidants in card...

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Detalhes bibliográficos
Main Authors: Savalia, Krupa, Manickam, Devika S., Rosenbaugh, Erin G., Tian, Jun, Ahmad, Iman M., Kabanov, Alexander V., Zimmerman, Matthew C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116739/
https://ncbi.nlm.nih.gov/pubmed/24924945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2014.06.001
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