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Binding of inhibitor alters kinetic and physical properties of extracellular cyclic AMP phosphodiesterase from Dictyostelium discoideum.

The extracellular adenosine 3',5'-cyclic monophosphate phosphodiesterase (3',5'-cyclic-nucleotide 5'-nucleotidohydrolase, EC 3.1.4.17) produced by Dictyostelium discoideum has two kinetic forms. The free enzyme has a Km of approximately 10 microM. The second form is the resu...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Kessin, R H, Orlow, S J, Shapiro, R I, Franke, J
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1979
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC411666/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/230476/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.11.5450
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