تحميل...
Quantitative network mapping of the human kinome interactome reveals new clues for rational kinase inhibitor discovery and individualized cancer therapy
The human kinome is gaining importance through its promising cancer therapeutic targets, yet no general model to address the kinase inhibitor resistance has emerged. Here, we constructed a systems biology-based framework to catalogue the human kinome, including 538 kinase genes, in the broader conte...
محفوظ في:
المؤلفون الرئيسيون: | , , , |
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التنسيق: | Artigo |
اللغة: | Inglês |
منشور في: |
Impact Journals LLC
2014
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الموضوعات: | |
الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4116514/ https://ncbi.nlm.nih.gov/pubmed/25003367 |
الوسوم: |
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