Haplotype Kernel Association Test as a Powerful Method to Identify Chromosomal Regions Harboring Uncommon Causal Variants

For most complex diseases, the fraction of heritability that can be explained by the variants discovered from genome-wide association studies is minor. Although the so-called ‘rare variants’ (minor allele frequency [MAF] < 1%) have attracted increasing attention, they are unlikely to account for...

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Main Authors: Lin, Wan-Yu, Yi, Nengjun, Lou, Xiang-Yang, Zhi, Degui, Zhang, Kui, Gao, Guimin, Tiwari, Hemant K., Liu, Nianjun
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116485/
https://ncbi.nlm.nih.gov/pubmed/23740760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21740
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