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Interaction of phencyclidine ("angel dust") with a specific receptor in rat brain membranes.
[3H]Phencyclidine binds to synaptic membranes from rat brain in a saturable, reversible, and selective fashion, with a dissociation constant Kd of 0.25 microM and a maximal binding capacity of 2.4 pmol/mg of membrane protein--i.e., 250 pmol/g of brain. The binding activity is concentrated in synapto...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1979
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC411644/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/41247/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.9.4678 |
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