Helicobacter pylori-induced posttranscriptional regulation of H-K-ATPase α-subunit gene expression by miRNA

Acute Helicobacter pylori infection of gastric epithelial cells induces CagA oncoprotein- and peptidoglycan (SLT)-dependent mobilization of NF-κB p50 homodimers that bind to H-K-ATPase α-subunit (HKα) promoter and repress HKα gene transcription. This process may facilitate gastric H. pylori coloniza...

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Main Authors: Zhang, Yong-Mei, Noto, Jennifer M., Hammond, Charles E., Barth, Jeremy L., Argraves, W. Scott, Backert, Steffen, Peek, Richard M., Smolka, Adam J.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2014
Assuntos:
Mucosal Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116396/
https://ncbi.nlm.nih.gov/pubmed/24503769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00333.2013
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