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Helicobacter pylori virulence factors affecting gastric proton pump expression and acid secretion

Acute Helicobacter pylori infection of gastric epithelial cells and human gastric biopsies represses H,K-ATPase α subunit (HKα) gene expression and inhibits acid secretion, causing transient hypochlorhydria and supporting gastric H. pylori colonization. Infection by H. pylori strains deficient in th...

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Détails bibliographiques
Publié dans:Am J Physiol Gastrointest Liver Physiol
Auteurs principaux: Hammond, Charles E., Beeson, Craig, Suarez, Giovanni, Peek, Richard M., Backert, Steffen, Smolka, Adam J.
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4525105/
https://ncbi.nlm.nih.gov/pubmed/26045613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00099.2015
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