Immunoglobulin differentiation is dictated by repeated recombination sequences within the V region prototype gene: A hypothesis
Analysis of the available DNA sequences of immunoglobulin light chain genes reveals a unique structural pattern. A stretch of about 15 nucleotides repeats five times within the variable (V) region gene, with few base changes. Identification of these homologous sequences is apparent in the embryonic...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteur principal: | |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1979
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC411626/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/116234/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.9.4598 |
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