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Immunoglobulin differentiation is dictated by repeated recombination sequences within the V region prototype gene: A hypothesis

Analysis of the available DNA sequences of immunoglobulin light chain genes reveals a unique structural pattern. A stretch of about 15 nucleotides repeats five times within the variable (V) region gene, with few base changes. Identification of these homologous sequences is apparent in the embryonic...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autor: Ben-Sasson, Shmuel A.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1979
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC411626/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/116234/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.9.4598
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