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NAC Attenuates LPS-Induced Toxicity in Aspirin-Sensitized Mouse Macrophages via Suppression of Oxidative Stress and Mitochondrial Dysfunction

Bacterial endotoxin lipopolysaccharide (LPS) induces the production of inflammatory cytokines and reactive oxygen species (ROS) under in vivo and in vitro conditions. Acetylsalicylic acid (ASA, aspirin) is a commonly used anti-inflammatory drug. Our aim was to study the effects of N-acetyl cysteine...

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Detalhes bibliográficos
Main Authors: Raza, Haider, John, Annie, Shafarin, Jasmin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116207/
https://ncbi.nlm.nih.gov/pubmed/25075522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103379
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