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Simultaneous Folding of Alternative RNA Structures with Mutual Constraints: An Application to Next-Generation Sequencing-based RNA Structure Probing

Recent advances in next-generation sequencing technology have significantly promoted high-throughput experimental probing of RNA secondary structures. The resulting enzymatic or chemical probing information is then incorporated into a minimum free energy folding algorithm to predict more accurate RN...

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Detalhes bibliográficos
Main Authors: Zhong, Cuncong, Zhang, Shaojie
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116156/
https://ncbi.nlm.nih.gov/pubmed/24689688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2013.0044
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